Publications

Found 6 results
Filters: Keyword is Protein Structure, Tertiary  [Clear All Filters]
2014
A. R. Stothert, Suntharalingam, A., Huard, D. J. E., Fontaine, S. N., Crowley, V. M., Mishra, S., Blagg, B. S. J., Lieberman, R. L., and Dickey, C. A., “Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma.”, Hum Mol Genet, vol. 23, no. 24, pp. 6470-80, 2014.
S. E. Hill, Donegan, R. K., and Lieberman, R. L., “The glaucoma-associated olfactomedin domain of myocilin forms polymorphic fibrils that are constrained by partial unfolding and peptide sequence.”, J Mol Biol, vol. 426, no. 4, pp. 921-35, 2014.
S. D. Orwig, Chi, P. V., Du, Y., Hill, S. E., Cavitt, M. A., Suntharalingam, A., Turnage, K. C., Dickey, C. A., France, S., Fu, H., and Lieberman, R. L., “Ligands for glaucoma-associated myocilin discovered by a generic binding assay.”, ACS Chem Biol, vol. 9, no. 2, pp. 517-25, 2014.
2012
R. K. Donegan, Hill, S. E., Turnage, K. C., Orwig, S. D., and Lieberman, R. L., “The glaucoma-associated olfactomedin domain of myocilin is a novel calcium binding protein.”, J Biol Chem, vol. 287, no. 52, pp. 43370-7, 2012.
R. K. Donegan and Lieberman, R. L., “New direction for glaucoma therapeutics: focus on the olfactomedin domain of myocilin.”, Future Med Chem, vol. 4, no. 17, pp. 2131-4, 2012.
2011
N. J Burns, Turnage, K. C., Walker, C. A., and Lieberman, R. L., “The stability of myocilin olfactomedin domain variants provides new insight into glaucoma as a protein misfolding disorder.”, Biochemistry, vol. 50, no. 26, pp. 5824-33, 2011.