Publications

Found 6 results
Filters: Keyword is Protein Binding  [Clear All Filters]
2014
A. R. Stothert, Suntharalingam, A., Huard, D. J. E., Fontaine, S. N., Crowley, V. M., Mishra, S., Blagg, B. S. J., Lieberman, R. L., and Dickey, C. A., “Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma.”, Hum Mol Genet, vol. 23, no. 24, pp. 6470-80, 2014.
S. D. Orwig, Chi, P. V., Du, Y., Hill, S. E., Cavitt, M. A., Suntharalingam, A., Turnage, K. C., Dickey, C. A., France, S., Fu, H., and Lieberman, R. L., “Ligands for glaucoma-associated myocilin discovered by a generic binding assay.”, ACS Chem Biol, vol. 9, no. 2, pp. 517-25, 2014.
2012
A. Suntharalingam, Abisambra, J. F., O'Leary, J. C., Koren, J., Zhang, B., Joe, M. Kuk, Blair, L. J., Hill, S. E., Jinwal, U. K., Cockman, M., Duerfeldt, A. S., Tomarev, S., Blagg, B. S. J., Lieberman, R. L., and Dickey, C. A., “Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism.”, J Biol Chem, vol. 287, no. 48, pp. 40661-9, 2012.
2011
R. L. Lieberman, Culver, J. A., Entzminger, K. C., Pai, J. C., and Maynard, J. A., “Crystallization chaperone strategies for membrane proteins.”, Methods, vol. 55, no. 4, pp. 293-302, 2011.
2009
M. R. Landon, Lieberman, R. L., Hoang, Q. Q., Ju, S., Caaveiro, J. M. M., Orwig, S. D., Kozakov, D., Brenke, R., Chuang, G. - Y., Beglov, D., Vajda, S., Petsko, G. A., and Ringe, D., “Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase.”, J Comput Aided Mol Des, vol. 23, no. 8, pp. 491-500, 2009.
R. L. Lieberman, J D'aquino, A., Ringe, D., and Petsko, G. A., “Effects of pH and iminosugar pharmacological chaperones on lysosomal glycosidase structure and stability.”, Biochemistry, vol. 48, no. 22, pp. 4816-27, 2009.