Found 8 results
Filters: Author is Orwig, Susan D [Clear All Filters]
“Structural basis for misfolding in myocilin-associated glaucoma.”, Hum Mol Genet, vol. 24, no. 8, pp. 2111-24, 2015.
, “Ligands for glaucoma-associated myocilin discovered by a generic binding assay.”, ACS Chem Biol, vol. 9, no. 2, pp. 517-25, 2014.
, “Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin.”, J Mol Biol, vol. 421, no. 2-3, pp. 242-55, 2012.
, “The glaucoma-associated olfactomedin domain of myocilin is a novel calcium binding protein.”, J Biol Chem, vol. 287, no. 52, pp. 43370-7, 2012.
, “Binding of 3,4,5,6-tetrahydroxyazepanes to the acid-β-glucosidase active site: implications for pharmacological chaperone design for Gaucher disease.”, Biochemistry, vol. 50, no. 49, pp. 10647-57, 2011.
, “Biophysical characterization of the olfactomedin domain of myocilin, an extracellular matrix protein implicated in inherited forms of glaucoma.”, PLoS One, vol. 6, no. 1, p. e16347, 2011.
, “Rescue of glaucoma-causing mutant myocilin thermal stability by chemical chaperones.”, ACS Chem Biol, vol. 5, no. 5, pp. 477-87, 2010.
, “Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase.”, J Comput Aided Mol Des, vol. 23, no. 8, pp. 491-500, 2009.
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