Found 39 results
Filters: Author is Lieberman, Raquel L [Clear All Filters]
“A blueprint for academic labs to produce SARS-CoV-2 RT-qPCR test kits.”, J Biol Chem, 2020.
, “Substrate-Enzyme Interactions in Intramembrane Proteolysis: γ-Secretase as the Prototype.”, Front Mol Neurosci, vol. 13, p. 65, 2020.
, “Antibodies Used to Detect Glaucoma-Associated Myocilin: More or Less Than Meets the Eye?”, Invest Ophthalmol Vis Sci, vol. 60, no. 6, pp. 2034-2037, 2019.
, “Differential Misfolding Properties of Glaucoma-Associated Olfactomedin Domains from Humans and Mice.”, Biochemistry, vol. 58, no. 13, pp. 1718-1727, 2019.
, “Exploring substituent diversity on pyrrolidine-aryltriazole iminosugars: Structural basis of β-glucocerebrosidase inhibition.”, Bioorg Chem, vol. 86, pp. 652-664, 2019.
, “How does a protein's structure spell the difference between health and disease? Our journey to understand glaucoma-associated myocilin.”, PLoS Biol, vol. 17, no. 4, p. e3000237, 2019.
, “Progranulin deficiency leads to reduced glucocerebrosidase activity.”, PLoS One, vol. 14, no. 7, p. e0212382, 2019.
, , “Atomic structure of a fluorescent Ag cluster templated by a multi-stranded DNA scaffold.”, J Am Chem Soc, 2018.
, “Consensus recommendations for trabecular meshwork cell isolation, characterization and culture.”, Exp Eye Res, vol. 171, pp. 164-173, 2018.
, “Contrast-Matching Detergent in Small-Angle Neutron Scattering Experiments for Membrane Protein Structural Analysis and Ab Initio Modeling.”, J Vis Exp, no. 140, 2018.
, “Progress toward development of a proteostasis drug for myocilin-associated glaucoma.”, Future Med Chem, vol. 10, no. 12, pp. 1391-1393, 2018.
, “Simulations and Experiments Delineate Amyloid Fibrilization by Peptides Derived from Glaucoma-Associated Myocilin.”, J Phys Chem B, vol. 122, no. 22, pp. 5845-5850, 2018.
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“Catalytic Properties of Intramembrane Aspartyl Protease Substrate Hydrolysis Evaluated Using a FRET Peptide Cleavage Assay.”, ACS Chem Biol, vol. 10, no. 9, pp. 2166-74, 2015.
, “Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions.”, J Med Chem, 2015.
, “Increased Fab thermoresistance via VH-targeted directed evolution.”, Protein Eng Des Sel, vol. 28, no. 10, pp. 365-77, 2015.
, “Molecular Details of Olfactomedin Domains Provide Pathway to Structure-Function Studies.”, PLoS One, vol. 10, no. 6, p. e0130888, 2015.
, “Structural and biophysical characterization of an epitope-specific engineered Fab fragment and complexation with membrane proteins: implications for co-crystallization.”, Acta Crystallogr D Biol Crystallogr, vol. 71, no. Pt 4, pp. 896-906, 2015.
, “Structural basis for misfolding in myocilin-associated glaucoma.”, Hum Mol Genet, vol. 24, no. 8, pp. 2111-24, 2015.
, “Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma.”, Hum Mol Genet, vol. 23, no. 24, pp. 6470-80, 2014.
, “The glaucoma-associated olfactomedin domain of myocilin forms polymorphic fibrils that are constrained by partial unfolding and peptide sequence.”, J Mol Biol, vol. 426, no. 4, pp. 921-35, 2014.
, “Ligands for glaucoma-associated myocilin discovered by a generic binding assay.”, ACS Chem Biol, vol. 9, no. 2, pp. 517-25, 2014.
, “Molecular basis of 1-deoxygalactonojirimycin arylthiourea binding to human α-galactosidase a: pharmacological chaperoning efficacy on Fabry disease mutants.”, ACS Chem Biol, vol. 9, no. 7, pp. 1460-9, 2014.
, “Determination of soluble and membrane protein structures by X-ray crystallography.”, Methods Mol Biol, vol. 955, pp. 475-93, 2013.
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