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The Barry lab generates new knowledge concerning protein-based catalysis. Research foci include the enzymes involved in oxygenic photosynthesis and DNA synthesis. This information will contribute to improvements in artificial solar energy conversion and in the treatment of disease. Students in the Barry lab develop and use a wide variety of biochemical and biophysical techniques, including spectroscopy, biomimetics, and chemical biology. The research is highly interdisciplinary and collaborative.
- Calcium, conformational selection, and redox-active tyrosine YZ in the photosynthetic oxygen-evolving cluster
- UV Resonance Raman Study of Apoptosis, Platinum-Based Drugs, and Human Cell Lines
- Engineering Proton Transfer in Photosynthetic Oxygen Evolution: Chloride, Nitrate, and Trehalose Reorganize a Hydrogen-Bonding Network
- Redox-Driven Conformational Dynamics in a Photosystem-II-Inspired β-Hairpin Maquette Determined through Spectroscopy and Simulation