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The Barry lab generates new knowledge concerning protein-based catalysis. Research foci include the enzymes involved in oxygenic photosynthesis and DNA synthesis. This information will contribute to improvements in artificial solar energy conversion and in the treatment of disease. Students in the Barry lab develop and use a wide variety of biochemical and biophysical techniques, including spectroscopy, biomimetics, and chemical biology. The research is highly interdisciplinary and collaborative.
- Proton-coupled electron transfer and a tyrosine–histidine pair in a photosystem II-inspired β-hairpin maquette: Kinetics on the picosecond time scale
- Reaction dynamics and proton coupled electron transfer: Studies of tyrosine-based charge transfer in natural and biomimetic systems
- A tyrosine–tryptophan dyad and radical-based charge transfer in a ribonucleotide reductase-inspired maquette
- Directly probing redox-linked quinones in photosystem II membrane fragments via UV resonance Raman scattering